First produced in Russia, Noopept became popular in the US and is now distributed worldwide. Noopept stands for N-phenylacetyl-L-prolylglycine ethyl ester. This is a nootropic molecule which provides a cognitive boost the same way piracetam works. Noopept also gives users a psychostimulatory effect. Apart from being acknowledged for its nootropic properties, in many countries, the drug is prescribed for disease and age-related cognitive decline. Here is a look at how Noopept works, as well as its effects, and dosage.
How Does Noopept Work?
The moment you introduce Noopept into your system, the drug is absorbed by the gastrointestinal tract and when it reaches your bloodstream, it crosses the blood-brain barrier. When it reaches your brain, Noopept binds itself to the receptors of a special neurotransmitter, glutamate neurotransmitter. The drug prevents the breaking down of glutamate while making your brain receptors more sensitive to it. Since glutamate is essential for supporting and expanding cognitive function, it a good thing that Noopept’s action is focused on this neurotransmitter.
In several animal-based tests, it was found that Noopept restores cognition. It was also found that the drug prevents the accumulation of pro-inflammatory cytokines and free radicals. Noopept also prevents excitotoxicity, neurotrophic deficit, and ionic imbalance. However, Noopept was only seen to affect impaired brains. For example, it was found that it was more beneficial to people with Alzheimer’s disease than those who had no brain injury.
Effects of Noopept
Most nootropics are known for their short and long-term benefits with little negative effects except for stomach distress and minor headaches. Noopept has a lower potential for side effects and is safe, needed in lower dosages, and has neuro protective effects that last long after you stop using the drug. The main downside of using this drug is that it has varying effects and benefits depending on the user. Some users experience a sudden change in their cognitive and memory abilities, while others experience a significant increase in their ability to remember small details.
Two animal studies linked Noopept with destroying the impact of learned helplessness in rats. This is considered to be a model of depression. The only human study assessing depression found that people suffering from brain injury were less depressed when given 20mg of Noopept for a few weeks. In another study on mice, Noopept was found to have a positive effect on users with Alzheimer’s and Parkinson’s disease.
Noopept also has a mild psychostimulatory effect. The nootropic has been seen to promote neuronal excitation, which is related to its psychostimulatory effect.
Noopept is closely related to and sometimes confused with racetam nootropics. Although the two have similar effects, Noopept is a peptide. The main distinction between Noopept and other nootropics is the speed with which it works. Many nootropics take days before the effects can be experienced, but with Noopept, the effects kick in almost instantly. Additionally, Noopept is highly potent. It is 1000 times stronger than piracetam. In some studies, it has been established that Noopept is 5,000 times stronger than piracetam.
Noopept is available in powder and tablet form. It has a lower dosage when compared to piracetam. The drug also has a neuroprotective effect long after you stop using it. While piracetam is offered in dosages of 4,800mg, Noopept only requires 10-30mg. The neuroprotective effects of the drug occur at various stages of cognitive trauma, which include physical trauma and oxidative stress. The recommended dosage is 30mg daily: one in the morning and one in the afternoon.